Studies

  • NCT04832932
  • NCT03451994
  • NCT03582826
  • NCT02692495
  • NCT02683876

    COVID-19

  • August Case Reports
  • July Case Reports
  • June Case Reports
  • May Case Reports

    Other Blog Posts

  • Vaccine Reactogenicity


    August 30, 2022: Spike protein in the skin after COVID-19 vaccination BNT162b2 vaccine reactivates Varicella Zoster, herpetic vasculitis skin leisons contain spike protein.


    August 23, 2022: Vaccine-related pneumonitis COVID-19 vaccine-related pneumonitis (CV-P) should be considered in patients with atypical lung infiltration, no specific etiologies, and recent COVID-19 vaccination. 11 cases with a median age of 80 are presented in the Korean Journal of Internal Medicine.

    August 22, 2022: COVID-19 Vaccine reactogenicity and breakthrough infections: decentralized participatory study A decentralized longitudinal study bridging digital divide identifies previously unreported patterns.

    August 20, 2022: Idiopathic nephrotic syndrome relapse following SARS-CoV-2 vaccination 25 cases (16 men/9 women) presenting a relapse of this rare kidney condition within one month of a COVID-19 vaccine injection are reported in the new issue of Clinical Kidney Journal.

    August 15, 2022: T-cell lymphoma after COVID-19 vaccination Reappearance of pre-existing cancers post COVID-19 vaccination was described in medical literature. A new publication reports a new-onset subcutaneous lymphoma in a young individual.

    August 10, 2022: A Fatal Breakthrough COVID-19 Case with prolonged high viral load An Asian man in his 70s died from breakthrough COVID-19 after 2 doses of mRNA vaccine.

    August 8, 2022: Minimal change disease after COVID-19 vaccination There have been a small but increasing number of cases of new-onset and relapse of glomerular diseases reported to have occurred in temporal association with the COVID-19 vaccines.

    August 6, 2022: Vogt-Koyanagi-Harada syndrome Vogt-Koyanagi-Harada (VKH) syndrome is an autoimmune, multi-systemic disease which can occur due to viral infection or vaccination. Several cases have been documented after COVID-19 vaccines.

    August 4, 2022: Vaccinated and boosted 75-year old dies from COVID-19 in the BA.5 wave He seemed to be recovering, but started to experience shortness of breath and was taken to the hospital.

    August 3, 2022: Thyroiditis after COVID-19 mRNA vaccines Subacute thyroiditis (SAT) is a thyroid inflammatory disease associated with viral infections. Its pathogenesis is still unclear. Several SAT cases associated with SARS-CoV-2 infection as well as COVID-19 vaccination have been reported.

    August 2, 2022: Another case of a teenager with severe adverse reactions after COVID-19 vaccination. 17-year old boy develops rash all over his body after his first shot of the BNT162b2 COVID-19 vaccine, dies one month later.

    July 26, 2022: Allergic reaction and myocardial infarction in a 91-year-old female First payment to a vaccine victim from the Japanese health ministry

    July 24, 2022: Prolonged Diarrhea after COVID-19 vaccination Up to 10% of individuals who received at least one dose of SARS-CoV-2 vaccine reported diarrhea as a side effect. This report describes case of diarrhea lasting longer than a month.

    July 18, 2022: Adverse Ocular Events After SARS-CoV-2 vaccines SARS-CoV-2 virus provokes an insult to every singleretinal structure, including retinal structures. Multiple cases of ocular inflammation after COVID-19 vaccines have been also reported.

    July 10, 2022: 59-year old woman dies from COVID-19 despite vaccination, boosting People are still dying Of Covid.

    July 9, 2022: 48-year old male dies days after receiving the AstraZeneca jab July 09, 2022 An inquest heard how he fell ill with a migraine, before his condition severely deteriorated in the following days.

    July 8, 2022: Postvaccinal Encephalopathy The occasional incidence of acute encephalitis following vaccination may be as old as the procedure itself. First noted in 1801, it was reported after vaccination against small pox, Hepatitis B, Influenza, Measles, Mumps and Rubella (MMR), and Haemophilus. We describe a case after a COVID-19 vaccine.

    July 7, 2022: Lack of SARS-CoV-2-specific cellular response despite apparent effective vaccination Measuring antibodies which bind viruses to tag them for destruction and antibodies which stop viruses from infecting cells by neutralizing them are associated with vaccine effectiveness. A new study indicates that c ellular response (T-cell proliferation and whole blood Interferon-Gamma Release assays) might provide a better measure.

    July 6, 2022: 72-year old woman dies from breakthrough COVID-19 shortly upon admission to a hospital She was fully vaccinated and boosted and was waiting for approval of a life-saving drug.

    July 5, 2022: Lower positivity rate among unvaccinated individuals compared to those who have received at least 1 dose of vaccine Measuring antibodies which bind viruses to tag them for destruction and antibodies which stop viruses from infecting cells by neutralizing them are associated with vaccine effectiveness. A new study indicates that c ellular response (T-cell proliferation and whole blood Interferon-Gamma Release assays) might provide a better measure.

    The more vaccinated you are (unless you got your last dose recently), the higher the chance you test positive?

    June 30, 2022 Omicron variants: Is vaccine effectiveness negative? New MedRxiv paper argues that the vaccine effectiveness for the third dose was in negative since December 20, 2021, with a significantly increased proportion of SARS-CoV2 cases hospitalizations and deaths among the vaccinated

    June 25, 2022: Myocarditis and Pericarditis following Covid-19 mRNA vaccines in French Population In line with results from a cohort study in Nordic countries, analyses of data from France show a significant risk and population burden of pericarditis following the second dose of the BNT162b2 and mRNA-1273 vaccines.

    June 24, 2022: Breakthrough COVID-19 fatalities after the 4th dose There were 39 COVID-19 related deaths among the fourth dose recipients in Israel yielding a cumulative mortality of 0.2%.

    June 23, 2022: Cardiovascular disorders after third dose Most cases of cardiovascular adverse events in vaccine recipients occur following the second dose. But severe reaction could happen even if the first and second dose did not cause any side effects.

    June 15, 2022: Hepatitis triggered by a complex interplay with SARS-CoV-2 vaccination Several cases of autoimmune hepatitis following COVID-19 vaccination have been previously described. This post discusses two more: in a 52-year-old woman undergoing immunotherapy and a 17-year-old woman exposed to SARS-CoV-2 after vaccination with a detectable immune response. Unusual epidemic of hepatitis in children has been widely reported in recent weeks. No one has a definite answer to its causes yet.

    June 13, 2022: Hypertensive Anaphylaxis after Moderna vaccine Acute onset of increased blood pressure after vaccination may be a premonitory symptom of anaphylaxis.

    June 12, 2022: Adverse Effects of Facemasks Many dermatological and neurological adverse effects of facemasks have been described in medical literature.

    June 8, 2022: Irreversible Cardiomyopathy Induced by COVID-19 Vaccination Irreversible cardiomyopathy was a result of the inflammatory process associated with SARS-CoV-2 infection and the subsequent cytokine storm from the vaccination.

    June 7, 2022: COVID-19 Vaccine-Associated Transient Amnesia Multiple cases of transient global amnesia (TGA) after the 1st, 2nd or 3rd dose of a COVID-19 vaccine have been observed in the elderly and younger populations.


    May 18, 2022: Long COVID symptoms don't resolve due to subsequent vaccinations A new study from Mount Sinai followed 453 COVID-19 patients with post-acute sequelae of COVID (PASC) 72% of got vaccinated in the following 6 months but this did not resolve anosmia, respiratory symptoms, depression, anxiety, PTSD, or quality of life.

    May 16, 2022: Resolving subtypes of COVID-19 in the elderly Patients with COVID-19 present a broad spectrum of clinical manifestations, ranging from asymptomatic infection to lethal outcome. Both the young and the old may have very different clusters of symptoms and responses to medications, including the COVID-19 vaccines. Each type is associated with how severe of an illness a patient might experience, ranging from asymptomatic to lethal.

    May 16, 2022: Fatal Breakthrough COVID-19 in a Heart Transplant Recipient A 71-year-old male is gdiagnosed with a breakthrough COVID-19 16 days after his second mRNA vaccine dose.

    May 13, 2022: Pericardial effusion as a complication of vaccination against COVID-19 Cases following vaccination in adults and fetuses after maternal COVID-19 vaccination

    May 12, 2022: Urological Adverse Effects of COVID-19 Vaccination More than 10% of individuals experience deterioration in storage lower urinary tract symptoms after COVID-19 vaccination

    May 10, 2022: Fatal autoimmune acquired factor XIII/13 deficiency after COVID‐19 vaccination A 78-year-old woman with no personal or family history of abnormal bleeding dies of CNS bleeding induced by her COVID-19 mRNA vaccination.

    May 6, 2022: Long Breakthrough COVID Cases of fully vaccinated and boosted individuals developing long COVID after breakthrough infection

    May 5, 2022: Fatal Guillain-Barré syndrome after COVID-19 vaccination A fit and healthy 77-year-old woman went from capable of loading firewood to being paralyzed after her 1st dose.

    April 30, 2022: Precision medicine for IBD A precision medicine approach discovers hidden genetic connections in Inflammatory Bowel Disease

    April 29, 2022: Increased cardiovascular emergencies during vaccine rollout Using a unique dataset from Israel National Emergency Medical Services (EMS) from 2019 to 2021, an increase of over 25% was detected in both cardiac arrest (CA) and acute coronary syndrome (ACS) EMS calls during January–May 2021, compared with the years 2019–2020

    April 28, 2022: 15-year-old boy commits suicide after cyberbullying for false rumor of being non-vaccinated A 15-year-old boy enrolled at a prestigious private school had a promising future — that is, until he became a victim of relentless cyberbullying by his classmates.

    April 25, 2022: Diabetes after COVID-19 vaccination Diabetes risk rises after COVID and, in some cases, after COVID-19 vaccination.

    April 20, 2022: On Cabbage and SELENBP1 Mutations in the gene encoding Selenium Binding Protein were found in multiple individuals with extra-oral halitosis.

    April 5, 2022: Fatal outcomes despite 4 COVID-19 vaccine doses COVID-19 vaccines reduce hospitalization and death, but they don't completely eliminate it, not even after four doses.

    April 1, 2022: April Fools' 2022 April Fools' Technology jokes can be prophetic or ominous, wishful thinking or a reflection of real concerns.

    March 31, 2022: COVID-19 Vaccine Effectiveness during Pregnancy We describe case series for pregnant women and discuss recent findings that pregnant individuals were 90% more likely to have been infected with coronavirus than the same number of people who were not pregnant, despite vaccination.

    March 27, 2022: Autoimmune skin conditions in the elderly after vaccination We discuss 29 cases of bullous pemphigoid with a median age 82.

    March 21, 2022: Passive Sensors for Health Monitoring Health data can be collected passively enabling continuous data collection and home-based trials.

    March 19, 2022: Long COVID and Adverse Effects of Vaccination in incontinentia pigmenti Patients with certain genetics are prone to more severe COVID-19, long COVID and adverse reactions to vaccination.

    March 11, 2022: Multisystem Inflammatory Syndrome in Children after SARS-CoV-2 Vaccination Multisystem inflammatory syndrome can follow SARS-CoV-2 infection, but it can be also induced by vaccination without current COVID-19 infection.

    March 6, 2022: Hearing Loss after COVID-9 Vaccination In a study of vaccinations in Israel, an association was found between the BNT162b2 mRNA COVID-19 vaccine and Sudden Sensorineural Hearing Loss. Similar case reports from other countries have been published in peer-reviewed journals.

    March 3, 2022: Getting Out of Echo Chambers We need critical thinking and cultural intelligence analysis skills to recognize the legitimacy and ongoing necessity of opposing views.

    February 28, 2022: Fatal outcomes in elderly patients after COVID-19 vaccination Many elderly individuals whose death was linked to the vaccine had preexisting cardiovascular diseases. Genetic predispositions could be also involved.

    February 20, 2022: Acute liver failure after COVID-19 vaccination A healthy 34-year-old health care worker with no history of COVID-19 dies from hepatic infarction a few days after his first dose of ChAdOx1nCov-19 vaccine.

    February 16, 2022: Catecholamine-Mediated Stress Cardiomyopathy after COVID-19 Infection & Vaccination An overly exuberant immune response to the vaccine can cause myocardial injury mediated by similar immune mechanisms as described with SARS-COV-2 and multisystem inflammatory syndrome (MIS-C) cytokine storms.

    February 15, 2022: Fatal breakthrough infections in solid organ transplant recipients 4 case reports of fatal breakthrough infections among liver and kidney transplant recipients aged 13-69.

    February 13, 2022: Fatal COVID-19 breakthroughs in kidney disease patients Brazilian and Scottish studies show that patients with kidney disease do not benefit from existing COVID-19 vaccines.

    February 2, 2022: Fatal COVID-19 breakthrough in an 88-year-old male Yet another report about a healthy person (except benigh prostate) who dies despite 2 doses of a COVID-19 vaccine

    February 2, 2022: Deaths of elderly individuals wrongly given an extra dose of the vaccine. They were given too many doses too soon - due to insufficient documentation or vaccine passport bureaucrats.

    February 1, 2022: Who benefits the least from COVID-19 vaccines? Vaccines help some people more than others.

    February 1, 2022: Vaccinated 71-year-old male dies from breakthrough COVID-19 on the 2nd day of symptom onset 71-year-old double-vaccinated overweight male started to feel unwell on the 7th day and died on the 9th day - while sitting in his easy chair shortly before an ambulance arrived.

    January 30, 2022: Severe breakthrough COVID-19 in vaccinated patients with multiple sclerosis. Multiple sclerosis patients have a higher risk of breakthrough infection

    January 21, 2022: Another case report on fatal breakthrough with brain involvement. Neurological manifestations are common in COVID-19. A sudden-onset reversible cerebral vasoconstriction syndrome (RCVS), possibly caused by a transient dysregulation of cerebral vascular tone, is described in this fatal COVID-19 vaccine breakthrough case.

    January 18, 2022: Fatal Anorexia caused by COVID-19 vaccination. A 90-year old woman in stable health receives the first dose of the COVID-19 vaccine, experiences inreased heart rate, develops anorexia and dies 28 weeks later.

    January 16, 2022: A fatal case of COVID-19 breakthrough infection in a 61-year old man A 61-year-old man with a history of arterial hypertension (PA 145/95 mmHg) and obesity with a body mass index (BMI) of 37.11 was vaccinated with a double dose of mRNA vaccine, but 4 months after the 2nd dose was diagnosed with COVID-19 and died 15 days after diagnosis despite treatment.

    January 13, 2022: Young COVID-19 vaccine breakthrough fatalities Vaccine effectiveness may fail for individuals with particular genetics and we need more studies and more medical case reports to develop personalized preventative and curative approaches.

    January 12, 2022: Post-infectious body odor A paper posted today on MedRxiv tells that dogs can easily detect long COVID - and not only acute COVID-19 - in at least half of the cases. Vaccine effectiveness may fail for individuals with particular genetics and we need more studies and more medical case reports to develop personalized preventive and curative approaches.

    January 8, 2022: Risk Factors for Severe COVID-19 Outcomes Among Vaccinated Individuals New Morbidity and Mortality Weekly Report (MMWR) emphasizes the usual risk factors for fatal breakthroughs: age 65 or older or at least one of these conditions: diabetes mellitus, immunosuppression, chronic kidney disease, chronic liver disease, chronic neurologic disease, chronic cardiac disease, or chronic pulmonary disease.